Detalhe da pesquisa
1.
Mice deficient in NRROS show abnormal microglial development and neurological disorders.
Nat Immunol
; 18(6): 633-641, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28459434
2.
Microglia in Brain Development, Homeostasis, and Neurodegeneration.
Annu Rev Genet
; 53: 263-288, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31518519
3.
Genome-Wide Analysis of Differential Gene Expression and Splicing in Excitatory Neurons and Interneuron Subtypes.
J Neurosci
; 40(5): 958-973, 2020 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831521
4.
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aß42:Aß40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
J Neurosci
; 40(9): 1956-1974, 2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980586
5.
Genetic ablation of Gpnmb does not alter synuclein-related pathology.
Neurobiol Dis
; 159: 105494, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34464706
6.
Intricate interplay between astrocytes and motor neurons in ALS.
Proc Natl Acad Sci U S A
; 110(8): E756-65, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23388633
7.
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Proc Natl Acad Sci U S A
; 109(15): 5803-8, 2012 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451909
8.
IκB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses.
Proc Natl Acad Sci U S A
; 108(52): 21170-5, 2011 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22171011
9.
TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice.
Elife
; 122023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37555828
10.
Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection.
Mol Ther Nucleic Acids
; 32: 773-793, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37346977
11.
TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models.
iScience
; 26(11): 108362, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37965143
12.
Disease-associated oligodendrocyte responses across neurodegenerative diseases.
Cell Rep
; 40(8): 111189, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001972
13.
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Nat Aging
; 2(9): 837-850, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118504
14.
TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Cell Rep
; 37(13): 110158, 2021 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965428
15.
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination.
Cell Rep
; 34(10): 108835, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33691116
16.
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by ß-amyloid pathology.
Neuron
; 109(8): 1283-1301.e6, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675684
17.
Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation.
Cell Rep
; 31(13): 107843, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610143
18.
Computed tomographic angiography of infants with congenital heart disease receiving extracorporeal membrane oxygenation.
Pediatr Cardiol
; 30(8): 1154-6, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19636487
19.
Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression.
Sci Rep
; 8(1): 16725, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425303
20.
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Neuron
; 100(6): 1322-1336.e7, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30392797